important One-Liners for FMGE Prepration
Subject :- Biochemistry
for more free study notes/free mock tests download our Android App from Google Play Store
1. In starvation there is an - Increase in Pyruvatekinase
2. Musty odour urine is seen in - Phenylketanuria
3. Vitamin necessary for post transitional modification - Vit.K
4. Decarboxylation needs - Vit.B6
5. Power house of the cell - Mitochondria
6. Protein synthesis takes place in - Endoplasmic reticulum
7. Daily secretion of bile by liver is amount of - 500-1000ml
8. Haemorhagic disease of Newborn is seen due to deficiency of - Vit.K
9. Acrodermatitis enteropathica is due to - Zinc deficiency
10. Molybdenum is necessary for - Xanthine oxidase
11. Hartnup disease is due to deficiency of - Tryptophan
12. Alkaptonuria is due to deficiency of - homogentisic acid oxidase
13. In alkaptonuria,the deposition of substance - Homocysteine
14. Vitamin used to correct neurological symptoms is - Cynocobalamine B12
15. Wernicke-korsakoff psychosis /Beriberi caused by defeciency of - Thiamine B1
16. Pellagra is caused by defeciency of - Niacin B3
17. Burning foot syndrome is caused by defeciency of - Pantothenic
18. Megaloblastic anemia/Neural tube defect caused by defeciency of - Folic acid
19. Pernicious anemia caused by defeciency of - B12
20. Sebhoric dermatitis caused by defeciency of - Riboflavin B2
21. IHD is associated with which type of cholesterol - LDL
22. Seen in chronic starvation - insulin decreases/glucagon & growth hormone
increases/free fatty acids increases/glucose tolerance decreases.
23. Southern blot test is used to detect - DNA
24. Northern Blot test - RNA
25. Western Blot test - Protein
26. Vitamin used for inhibiting lactation - B6
27. Wernicke’s encephalopathy is caused by defeciency of - B1
28. Vitamin K dependant clotting factors are - fac.2,7,9,10
29. Enzyme defecient in marfan’s syndrome is - Lysyl oxidase
30. Reactions takes place in Mitochondria - krebs cycle,urea cycle,electron transfer,fatty acid cycle
31. Melatonin is synthesised from - Tryptophan
32. Amino acids excreted in the urine in cystinosis - cystine,ornithine,arginine,lysine
33. In maple syrup urine dis. the aminoacids excreted n urine r -leucine,isoleucine,valine
34. Sulphur containing amino acids -cysteine & methionine
35. Conjugated hyperbillirubinemia s seen -Dubin jhonson synd.
36. In Hartnup’s disease excreated in urine is- Tryptophan
37. Bile contains - cholic acid,chenodeoxycholic,deoxycholic,lithocolic acids
38. Cofactor for transamination is - Pyridoxine
39. Vitamin essential for transamination - B6
40. Phenyl pyruvic acid in the urine is detected by - Guthrie’s test
41. In alkaptonuria the urine contains - Homogentisic acid
42. Insulin has - 51 amino acids
43. Von gierke’s disease is due to defeciency of - galactose-1-phosphate uridyltransferase
44. Essential fatty acids are - linoleic,linolenic & arachidonic acid
45. Iron is absorbed actively in the - Duodenum
46. vit.B12 is absorbed in the - Terminla ileum
47. Highest content of triglycerides is seen in - Chylomicrons
48. Atherosclerosis is due to - Apo protein E defeciency
49. Triglyceride synthesis is increased by - Insulin
50. Which is an essential amino acid - phenylalanine,lysine,leucine
51. Insulin acts on which enzyme in glycolysis - Glucokinase
52. Present in cerebroside - Sphingosine,galactose
53. Melatonin is derived from - Tryptophan
54. Liver produces - albumin,fibrinogen,prothrombin & not gamma globulin
55. Bile acids are formed from - cholesterol
56. Heme in hemoglobin is in the - Hydrophobic pocket
57. 17-Alpha hydroxylase defeciency causes - decreased testosterone
58. Substance that does not cross blood brain barrier - Insulin
59. Anti infective vitamin is - vitamin A1
60. Tissue with highest glycogen content - Liver
61. Detoxification of drugs is controlled by - cytochrome P450
62. Anti atherosclerotic lipoprotein is - HDL
63. MC enzyme defeciency in man is - glucose-6-phosphate dehydrogenase
64. Largest amounts of prostaglandins are seen in - Seminal fluids
65. Sulphonamides are conjugated by - Glucoronic acid
66. Which amino acid causes Hypoglycemia - Leucine
67. Vitamin present in co-enzyme A is - pantothenic acid
68. Insulin resistance is seen in - hypothyroidism,acromegaly
69. Fatty acid not synthesised in the body is - linoleic acid
70. Albinism results from deficiency of - Tyrosinase
71. Enzymes stored in muscle is- CPK
72. Secondary hyper parathyroidism is caused by - CRF
73. Abnormal Urinary constituents are - albumin, ketone, glucose
74. Urinary constituents - amino acids, urea, creatinine
75. Polyuria is seen in - DM,diabetes insipidus,recovery from acute nephritis
76. Polypeptide hormones are - insulin,angiotensin,growth hormones
77. Physiological constituents of urine - urea,creatinine
78. Major site of action of insulin - muscle,adipose tissue liver
79. Semi essential aminoacids are - Arginine,histidine
80. Ratio of adrenaline to noradrenaline - 85:15
81. Examples of monounsaturated fatty acids are - oleic acid
82. Acidic amino acids are - asparagine,glutamine
83. Basic amino acids are - arginine,lysine
84. Aromatic amino acids are - tryptophan,tyrosine,phenylalanine
85. Total body iodine stores are about - 50mg
86. vit.C is present in largest amount in the body in - Adrenal cortex
87. Tetany can be caused by - hypocalcemia,hypomagnesemia
88. Ketone bodies are - Acetoacetate
89. Bile acids are derived from - cholesterol
90. Which is completely dependant on glucose as fuel - Retina
91. Immediate precursor of nor epinephrine is - Dopamine
92. Uric acid levels are increased in - pre-eclampsia,hodgkins lymphoma,leukemia
93. Metal in vit.B12 is - Cobalt
94. Ammonia in the brain is converted into - Glutamine
95. Dopamine synthesis in brain is increased by - Carbidopa
96. Calcium binding protein is - Troponin-C
97. Metabolite of epinephrine is - Metanephrine
98. End product of purine metabolism is - Uric acid
99. Vitamin A overdosage causes injury to - Lysosomes
100. Myocardium normally utilises - Fatty acid
101. Max. amount of serum cholesterol is found in - LDL
102. Vitamin that is useful in cancer is vitamin - A
103. Enzyme acetylcholine esterase is synthesised in - Liver
104. Urea in the Brain is derived from - Glutamine
105. Non-essential aminoacid is - Tyrosine
106. Enzyme primarily responsible for protein degradation in stomach - Pepsin
107. Increased anion gap is seen in - renal failure, lactic acidosis, DKA
108. Cholesterol from the liver is transported to the tissues mainly by the - VLDL
109. Precursor of steroid - cholesterol
110. Maple syrup urine disease is due to the deficiency of - Decarboxylation
111. Amino acid that can be converted into vitamin is - tryptophan
112. Main function of mitochondria is - electron transfer
113. Histamine is produced by - decarboxylation
114. Glutathione is a - tripeptide
115. Ketone body formation takes place in - liver
116. Xantheurenic acid is a product of metabolism of - Tryptophan
117. Neurotransmitter is - Glutamine
118. DNA double helix is bound by - Hydrogen bond
119. Glucose-6-phosphate dehydrogenase deficiency is seen in - vongierke’s disease
120. Which is not seen in starvation - hypercholesterolemia
121. Muscle glycogen is mainly used for supplying energy to - heart
122. Enzyme marker of electron transport system is - cytochrome reductase
123. Major contribution towards gluconeogenesis is by - Alanine
124. Conversion of prothrombin to thrombin requires - factors-7,10,5 & Ca2+
125. Which does not inhibit platelet aggregation - Thromboxane A2
126. Conversion of proline to hydroxyproline is by - vit.C mediated hydroxylation
127. Ketone body which is maximum in DKA - Acetoacetic acid
128. Biotin is essential for - carboxylation
129. Ketoacidosis without glycosuria is seen in - prolonged starvation
130. Protein synthesis takes place in - Endoplasmic reticulam
131. NADPH is required in - lipogenesis
132. Dietary fibre is rich in - Pectin
133. Lipid which accumulates in fatty liver is - Triglycerides
134. Gluconeogenesis occurs in the- liver & Kidney
135. Germ oil has high content of vitamin - E
136. Melanin is synthesised from - phenylalanine
137. Obesity is associated with - decreased insulin response
138. Glycerol is converted to glucose in - Liver
139. vit.K plays an essential role in - biosynthesis of prothrombin & proconvertin
140. Preservative used in urine samples for chemical analysis is - Thymol
141. Heart muscle in comparison to skeletal muscle has - high carnosine
142. pH of normal sweat is - 4.5
143. Urea is mainly formed in liver & to small extent in - Brain
144. Pantothenic acid acts on - CoA
145. Fluoride ions act by inhibiting - Enolase
146. Deficiency of which vitamin is not known in newborn - E
147. Toad skin is seen in deficiency of vitamin - A
148. Resting membrane potential is close to the isoelectrical potential of - Cl
149. Infant’s gastric juice pH is - 5.0
150. Enzyme diagnostic of MI in acase of hypothyroidism - CPK-MB
151. Transaminase an enzyme is most abundant in - Heart
152. White hair is due to - deficiency of melanin
153. Anticoagulant used for preserving blood for PT estimation is - sodium citrate
154. Biotin deficiency is characterised by - muscular pain, nausea, dermatitis
155. Zinc is a component of - carbonic anhydrase,insulin,carboxypeptidase
156. Respiratory quotient of fat, protein & carbohydrate are - 0.70-0.80-1.0
157. In glycolysis which of the ions is most important - Mg
158. Prostaglandins - are acyclic fatty acid derivatives
159. Thiouracil inhibits thyroid function by - inhibition of thyroxine synthesis
160. Cytochromes are - iron-porphyrin proteins
161. Vitamin acts as a respiratory catalyst - vit.C
162. Histidine decarboxylase is present in - liver & kidney
163. Dietary changes are not required in - wilsons disease
164. Codon consists of - 3 consecutive nucleotide units
165. Coenzymes are - non-protein organic compounds
166. Hair is rich in amino acid - Cystine
167. Component of co-enzyme A - pantothenic acid,adenylic acid,sulphydryl group
168. Renin is present in - stomach
169. Methionine is important in - formation of choline
170. Actinomycin D interferes with enzyme induction by combining with - DNA
171. Ketone bodies are by products of metabolism of - Fats
172. Lactate dehydrogenase is - Isozyme
173. Creatinine is formed metabolically from - Arginine
174. Blood brain barrier is maximally permeable to - CO2
175. Which of the following vitamin is destroyed by heat - Biotin
176. Daily normal excretion of ketone bodies - 1.0mg
177. Hexokinase is a - Transferase
178. Which is the by product of the urea cycle - Fumarate
179. False positive reaction of glucose is seen with - Aspirin
180. Which of the following is not a trace element - Ca+
181. Chitin is a - Polysachride
182. Biuret test is mainly done for - Protein
183. In metabolic acidosis, true about urinary change is - increase in Ammonia
184. Monoclonal electrophoresis is useful in the diagnosis of - Multiple myeloma
185. Basic structural unit from which fatty acids are derived - Acetyl Co A
186. Precursor of cholesterol synthesis is - Acetyl CoA
187. Whole wheat is an excellent source of - Thiamine
188. Siderophyllin is - transferrin
189. Which of the following is not a phospholipid - cerebroside
190. Triglycerides in serum are transported by -VLDL
191. Which of the following is a initiating amino acid for protein synthesis - Methionine
192. In mammalian cells protein sequence takes place chiefly at the - nucleolus
193. Insulin resistance may be due to - Acromegaly
194. Cytochromes are - iron-porphyrin proteins
195. Which of the following is seen in obstructive jaundice - excess of bile salts in
the urine
196. Which of the following cannot be metabolized in the body - sucrose
197. High threshold substance is - glucose
198. Million’s test is used for detection of - Tyrosine
199. HMP shunt great importance in cellular metabolism because it produces - NADPH
200. Urea is produced by the enzyme - Arginase
201. Actinomycin D interferes with enzyme induction by combining with - DNA
202. A bi-lipid layer is most permeable to - Urea
203. The lactate dehydrogenase levels are increased in - Glycine
204. The most direct precursor of taurine is - Cysteine
205. Aromatic ring is present in - phenylalanine
206. A substance having affinity but no intrinsic activity is - Antagonist
207. Ferritin an inactive form of iron is stored in - liver
208. First product of glycogenolysis is - glucose-1-phosphate
209. C-AMP increases glycogenolysis by - contributing phosphate
210. Bohr effect is - effect of PCO2 on oxyhemoglobin dissociation
211. Tea and coffee contains - tannin
212. Specific dynamic action is- energy expenditure on consumption of foods
213. Ingestion of benzoic acid in man results in an increase in urinary- hippuric acid
214. An essential amino acid in man is- L- methionine
215. The mucopolysaccharide hyaluronic acid is found primarily in - vitreous humor
216. An amino acid not involved in urea synthesis is- histidine
217. The most abundant protein in the human body is - collagen
218. Sorbitol is- sugar alcohol
219. Dicumarol is an antimetabolite of- vit K
220. Inhibition of glycolysis by O2 is known as- Pasteur effect
221. In human body which of the following trace element in next to iron- Cu++
222. Which of the following is a dietary essential- linoleic acid
223. Patients with severe renal disease may not be able to use normal dietary sources of vitamin- D
224. Winslow test is used to estimate serum or urinary- amylase
225. PH is maximum in- pancreatic secretion
226. Dawn phenomenon refers to -after breakfast hypoglycemia
227. Ehrlich’s test done to detect- urobilinogen
228. Benzidine test is positive with the enzyme- peroxidase
229. Cyanide is toxic because it- inhibits cytochrome oxidase
230. The substance essential for transfer fatty acids across mitochondrial membrane
231. carnitine
232. Which of the following organs can’t use ketone bodies- liver
233. Lipid from tissues is carried to liver by - HDL
234. Unsaturated fatty acids are converted to - Prostaglandins
235. Vitamin necessary for CoA synthesis - Pantothenic acid
236. Lamin is present in - inner nuclear membrane
237. NADPH is used in - Fatty acid synthesis
238. People eating only maize as staple diet develop niacin deficiency due to - high
leucine
239. Thromboxane is mostly produced by - Platelet
240. Alcohol-uric jaundice is caused by - hemolytic jaundice
241. Triple helix is seen in - collagen
242. Urinary protein is detected by - Barfoed test
243. Glutathione peroxidase contains - selenium
244. Cholesterol is a - steroid
245. Saturated fatty acid is present in high quality - coconut oil
246. Keratin is chemically - cystine
247. Untreated diabetes leads to - tissue use fatty acids as main fuel
248. MCC of lactic acidosis - Circulatory failure
249. Not a cause of metabolic acidosis - climbing to high altitudes
250. Vitamin also acting as hormone - Vit D
251. Proteins binding to DNA has - Zinc
252. DNA fragments are separated by - agarose gel electrophoresis
253. Ferritin stores are present in sites - intestine/liver/spleen but not in - bone
254. Osmolarity is - moles per liter of solvent
255. In Beri-Beri which enzyme activity is measured - Transketolase
256. An exclusive protein meal intake will cause - Hypoglycemia
257. Heart uses one of the following as energy source during starvation - Acetoacetate
258. In Maple syrup urine absence FeCl3 test with urine gives colour - Blue
259. Carnitine is formed from - Lysine
260. Arthritis occur in - Alkaptonuria
261. Norepinephrine is converted to epinephrine by - N-methylation
262. Most important compensatory mechanism in metabolic acidosis - Hyperventilation
263. Translation occurs at - Ribosome
264. The reaction inhibited in thiamine defeciency is - pyruvate to acetyl CoA
265. Skeletal muscle is deficient in - glucose -6-phosphate
266. Familial hypercholesterolemia is - deficient of LDL receptors
267. Cholesterol maximally carried in - LDL
268. Most abundant collagen in body is - Type-1
269. What is the technique by which DNA can be amplified - polymerase chain reaction
270. Null mutation is - mutation which produces no functional gene product
271. Which one is non sense codon- UAG,UGA
272. Which of the following amino acid ss assoc. with increased risk of MI - Homocysteine
273. Glutathione peroxidase contains - selenium
274. Which one of the following enzyme use NADP as co-enzyme - G6PD
275. Fatty acids of cholesterol are mainly - palmitic & stearic acid
276. Shortest peptide is - encephalin
277. FIGLU is a metabolite of - Histidine
278. Which is a fructosan - Inulin
279. Saponification means hydrolysis of fats by - Alkali
280. In pregnancy amount of glucose used in GTT - 100mg
281. Total number of genes in a human being is - 50,000
282. Naturally occuring amino acid - hydroxyproline
283. Northern blot is - amplification of mRNA
284. Source of ammonia in urine is - Glutaminase
285. Bilirubin is produced from - hemoglobin/myoglobin
286. Pyruvate utilization in tissues is decreased in - Beri-Beri
287. Amino acid used in the synthesis of purines - Glycine
288. In porphyria cutanea tarda the type of porphyrin excreted in urine is -type 1&3
uroporphyrins
289. Chromosomal nomenclature is based on - position of centromere
290. Not seen in - thiamine deficiency - cerebellar dysfunction
291. Warm auto antibodies are seen in - SLE
292. Xeroderma pigmentosum is produced as a result of defect in - DNA ligase
293. Fatty acids does not produce glucose due to absence of -phosphophenolpyruvatekinase
294. Best indicator of iron deficiency - serum ferritin
295. Chylomicrons belong to group - Apo-B
296. In the fasting state glucose is obtained from - muscle glycogen
297. Steroid biosynthesis occur at - smooth endoplasmic
298. Ketone bodies are formed in the - Liver
299. New DNA synthesis occurs in - interphase
300. Membrane phospholipid that does not contain glycerol is - Sphingomyelin
301. Antioxidants - vit A,C,E
302. End-product of the action of salivary amylase is – Maltose
303. Severe muscular exercise causes - Lactic acidosis
304. Vitamin A is stored mainly as retinol esters in - liver
305. Idiopathic nyctalopia is due to a hereditary - absence of rod function
For MCQ's of Biochem Click here>>>
Free Study Notes for FMGE find here>>>>
WhatsApp Group
if you want to download this pdf then refresh this page to unlock the DOWNLOAD OPTION
(please note- only first 2 visitors can download this pdf EVERYDAY
So even after refreshing the page 2-3 times , DOWNLOAD page is not opening, then try next day
